Comparative Hepatitis B Vaccine study

Why are we doing this study: The Comparative Hepatitis B Vaccine study is evaluating the safety and effectiveness of a newer Hepatitis B vaccine against the currently approved Hepatitis B vaccine. This will be a randomized multi-site clinical trial involving adults age 18 years and older.

The study involves: The participants of this study will receive 3 doses of the approved vaccine or the study vaccine over 3 visits. Blood tests will be taken at all visits. There will be a total of 7-10 visits over a 12 month period.

Dr. Manish Sadarangani named Sauder Chair in Pediatric Infectious Diseases

Congratulations to the VEC Director Dr. Manish Sadarangani on his recent appointment as the Sauder Chair in Pediatric Infectious Diseases at the University of British Columbia. Funded by a donation from the Sauder Family, the Chair supports research to improve the prevention, diagnosis and treatment of childhood infectious diseases.

When it comes to saving the lives of kids with serious infections, Dr. Sadarangani believes “the best option is prevention.”

 This new Chair will enable Dr. Sadarangani to further laboratory, clinical and population-based studies aimed at:

  • Understanding the immune response to vaccines
  • Developing new vaccines
  • Evaluating vaccine programs at the population level
  • Examining the incidence, causes and effects of serious childhood infections

To read more, click here.

Long Term Memory to HPV vaccine study

Participants needed: Women who have received either 2 or 3 doses of the HPV vaccine 8 to 10 years ago.

Why are we doing this study: Human Papillomavirus (HPV) is a common virus that can cause genital warts and can lead to cervical cancer. HPV is often described as the most common sexually transmitted infection. Vaccination with the HPV vaccine Gardasil® is known to be very good at  preventing HPV types 6, 11, 16 and 18. More research into the long term protection and immune memory years after vaccination with HPV vaccine is needed to make sure the females we vaccinate as girls are still protected as adults.

Although memory response or ‘protection’ can be measured soon after you get the HPV shot, the best way to measure long lasting protection is to give another dose, or a ‘booster’ of the vaccine years after the original shots. This is like a reminder to see how well your immune system remembers the HPV shot. We are therefore studying the immune system’s response to the HPV vaccine, 8 to 10 years after first dose. Continue reading “Long Term Memory to HPV vaccine study”

Celebrating Immunization: National Immunization Awareness Week 2017

NATIONAL IMMUNIZATION AWARENESS WEEK (#NIAW2017)

April 22nd - 29th, 2017
The VEC is celebrating National Immunization Awareness Week, an annual event to recognize the importance of immunization, by sharing a selection of our research highlights and news. You can read each story by clicking the links below

Human Vaccines Project to accelerate the development of vaccines


BC Children’s Hospital opening Canada’s first onsite immunization clinic in 2017


Cytomegalovirus (CMV) vaccine


Understanding why some parents are hesitant about vaccines


Early life immune system


Read our annual VEC newsletter here (and subscribe to the newsletter here!)

Human Vaccines Project: Help us better understand how the immune system responds to Hepatitis B vaccine!

Why we are doing the study:
Our overall goal is to understand why some people respond better to vaccines than others, a step towards making better vaccines to prevent against infections. With this study, we are looking into how the immune system responds to Hepatitis B virus (HBV) vaccine. This vaccine is widely used to prevent liver infection, a risk at all ages. Continue reading “Human Vaccines Project: Help us better understand how the immune system responds to Hepatitis B vaccine!”

March 29th: Vaccine Safety Surveillance in Pregnancy and Healthcare Providers’ Perceptions

Wednesday, March 29th, 2017
BCCHR Room 2108 | 12:00 – 1:00 pm

Title:Vaccine Safety Surveillance in Pregnancy and Healthcare Providers’ Perceptions”

Presenter: Dr. Karina Top, MD, MS
Assistant Professor of Pediatrics and Community Health & Epidemiology
Canadian Center for Vaccinology
Dalhousie University

 

Immunization Information & New Mothers Study

Participants needed: New mothers who live in the North and South Surrey, White Rock, Cloverdale, Newton and Guildford communities

Why are we doing this study: This study seeks to understand the ways in which new mothers obtain, share and use health information, especially information related to child vaccinations.

Focused in the North and South Surrey, White Rock, Cloverdale, Newton and Guildford communities, the study uses observation and interviews to explore how new mothers in these areas access information to make decisions about their babies’ health and immunizations. Continue reading “Immunization Information & New Mothers Study”

BC Children’s Hospital to open Canada’s first onsite immunization clinic

“In 1995, Dr. David Scheifele wrote a paper proposing that facilities such as B.C. Children’s Hospital should have on-site clinics where sick kids could catch up on their vaccinations. It took 21 years, but that vision is finally becoming a reality.” – The Vancouver Sun, click for article

In the Fall of 2017, BC Children’s Hospital will open the doors to Canada’s first onsite immunization clinic. The clinic will provide immunizations at no cost to children, youth and their family members visiting BC Children’s.

“This is a fantastic opportunity to protect some of the most vulnerable children in our society who come through the doors of BC Children’s Hospital every day. Offering immunizations to all family members is a simple and highly effective way to extend the impact of the clinic.” – Dr. Manish Sadarangani

For four years, the VEC has been a part of the BC Children’s on-site family flu immunization clinic offering free flu immunizations to families visiting the hospital during the months of November and December. The flu clinic has set the foundation for an onsite immunization clinic, making immunizations as accessible as possible for families and in reaching across age barriers to maximize protection of vulnerable children.

The new immunization clinic has been made possible by a generous $15 million donation from Save-On Foods.

To read the full story, click here.

Safety surveillance of the influenza vaccines

An annual flu vaccine safety survey is completed by over 20,000 people across Canada who receive their flu vaccine. The purpose of the online survey is to monitor adverse events (side-effects) after the flu shot and allows us to monitor the safety of the flu vaccine used in Canada each year.

Dr. Julie Bettinger presents findings from the safety survey at the Canadian Immunization Conference 2016. Of 200 abstracts, this study was chosen as one of the Top 10 Scientific Abstracts of 2016.

In 2015, nearly 15,000 adults responded to the online survey, most did not report any health events after the flu shot. 95% of the unvaccinated control group did not report a health events compared to nearly 97% of the vaccinated group. Overall, no safety concerns were detected for the 2015 flu vaccines.

For more information and to read the abstract, click here

This project is being conducted by Canadian National Vaccine Safety (CANVAS) network. 2016 marks the 6th year of the Vaccine Safety Survey.

Co-authors: Louis Valiquette, Brenda Coleman, Karina Top, Otto Vanderkooi, Anne McCarthy, James Kellner, Jennifer Isenor, Gaston De Serres