Why we are doing the study:
Our overall goal is to understand why some people respond better to vaccines than others, a step towards making better vaccines to prevent against infections. With this study, we are looking into how the immune system responds to Hepatitis B virus (HBV) vaccine. This vaccine is widely used to prevent liver infection, a risk at all ages.
Researchers at the VEC and the University of British Columbia will study in fine detail how the different parts of the immune system interact to protect against infection after this vaccine. This study is part of a large international collaboration called the Human Vaccines Project: Transforming How We Treat and Prevent Disease:
Its goal is to speed up development of vaccines against major infectious diseases around the world by “decoding” the human immune system; learning the deeper secrets of how vaccines work.
We are looking for:
Males and females ages 40 to 80 years in general good health who have never had the hepatitis B vaccine or infection.
The study involves:
12 visits over 8 months (about 11-13 hours of your time). Participants will receive 3 standard doses of the Hepatitis B vaccine. Visits will include blood tests, swab collections and small samples from the lymph node in the armpit. These tests are being done to examine everything that happens in the immune system between receiving a vaccine and developing protection.
You will receive:
Eligible participants will be reimbursed for travel/parking and an honorarium at each visit.
To learn more and to see if you are eligible to participate, please contact us.