CMV Vaccine Study

Participants needed: This study is looking for generally healthy women who are 16 to 35 years of age.

Why are we doing this study: CMV is a common virus that can infect anyone. Most people don’t know they have CMV because it rarely causes symptoms. However, if you are pregnant or have a weakened immune system, CMV is cause for concern as it can cause serious disease. Newborns infected with CMV can develop permanent disabilities such as deafness and mental disability. There is no cure for CMV so researchers at the Vaccine Evaluation Center would like to evaluate the safety and effectiveness of a newer vaccine to protect women against CMV, as well as their babies if they become pregnant.

The study involves: Participants will be randomly assigned to receive either a vaccine to protect them against CMV or a placebo. There will be 8 visits to the study clinic that will include a physical exam, vaccinations, blood tests, questions about the participant’s health, and more. Total time commitment is 9 to 10 hours spread over the course of 18 months to 3 years, depending on when participants enter the study.

You will receive: Eligible participants will be reimbursed for travel/parking costs for each visit to the clinic and for their time.

Continue reading “CMV Vaccine Study”

Meningococcal Vaccine Study

Participants needed: Healthy teenage boys and girls who are going into Grade 9

Why are we doing this study: Meningococcal disease is caused by Neisseria meningitidis and can result in severe disease such as septicemia (blood poisoning) and meningitis. There are currently 3 different vaccines being offered to teenagers across Canada and researchers at the Vaccine Evaluation Center would like to find out if there are any differences between these 3 vaccines, and if any of them are better than the others.

The study involves: There will be 3 visits to the study clinic over the course of one year. These visits will include a physical exam, vaccinations, blood tests, and questions about the participant’s health. Total time commitment is 3-4 hours. Participants will be randomly assigned into 1 of 3 Study groups, and will receive both the MenACWY and Tdap vaccines. These vaccines are part of the routine immunization schedule offered already in our public & private schools by public health for Grade 9 students in B.C.

You will receive: Eligible participants will be reimbursed for travel/ parking and receive a gift card at each visit.

See if you are eligible: Click here and fill out a short 3 minute survey

Continue reading “Meningococcal Vaccine Study”

Midwives’ Immunization Practices Survey

Researchers at the University of British Columbia’s (UBC) Vaccine Evaluation Center and the BC Center for Disease Control want to better understand how BC midwives understand their role as vaccination providers for their pregnant and post-partum clients.

The 20 minute online survey asks about what midwives do in their practice in regards to discussing, recommending, and administering vaccinations to pregnant and postpartum clients.

Results of this research will be used for public health decision making and will be presented at the BC College of Midwives, the BC Immunization

Committee, and might be published in professional journals

Questions?

Email us at crubincam@bcchr.ubc.ca.

The study is being sponsored by the BC Immunization Committee.

Unpacking Vaccine Hesitancy Among Perinatal Healthcare Providers

Pregnant women and new parents consistently report that they trust their maternity care providers and wish their health care providers had given them advice on immunization. However, perinatal health care providers may not recommend vaccines due to lack of confidence or other barriers.

Researchers at the University of British Columbia’s (UBC) Vaccine Evaluation Center and with the Canadian Immunization Research Network are working to better understand what would help perinatal healthcare providers confidently recommend routine immunizations in pregnancy and for infants.

The first phase of this study is currently underway. Selected perinatal healthcare providers in 6 provinces are being invited to participate in telephone interviews about their education and clinical practice.

Questions?

Email us at vecstudies@bcchr.ubc.ca.

This study is being sponsored by the Canadian Institutes of Health Research and the Canadian Immunization Research Network.

 

RSV Vaccine Study

Participants needed: Healthy babies age 12 to 23 months.

Why are we doing this study: Respiratory Syncytial Virus (RSV) is a virus that can cause infection in the airways.  Symptoms of RSV infection are like the common cold, such as runny nose, cough, sneezing.  There is currently no vaccine to treat RSV.  Researchers want to learn more about a new RSV vaccine that may potentially protect infants from RSV disease.

The study involves: 12 visits over 24 months.  Visits to the study clinic will include a blood test at each visit, questions about your baby’s health, physical exam, nose swabs, and 2 vaccinations.

You will receive: Eligible participants will be reimbursed for travel/ parking with a $40 honorarium at each visit.

Continue reading “RSV Vaccine Study”

Pneumococcal Vaccine Study

Participants needed: Babies at 2 months of age who were born healthy and at term (at least 37 weeks’ gestation).

Why are we doing this study: Pneumococcal disease is caused by the bacteria Streptococcus pneumoniae (SP). Although the vaccine is given as 3 shots at 2, 4, and 12 months of age, researchers would like to find out if it is possible to achieve the same protection using just 2 shots at 2 and 12 months.

The study involves: 6 visits over 11 months. Visits to the study clinic will include a blood test at each visit, poop samples, vaccinations at 2 and 12 months of age or vaccinations at 2, 4, and 12 months of age and questions about your baby’s health.

You will receive: Eligible participants will be reimbursed for travel/ parking and receive an honorarium at each visit.

Continue reading “Pneumococcal Vaccine Study”

Comparative Hepatitis B Vaccine study

–Recruitment closed–

Participants needed: Males and females age 18 years and older in good general health who have never received the Hepatitis B vaccine

Why are we doing this study: Hepatitis B virus (HBV) is a virus that attacks the liver and can lead to cancer. The currently approved HBV vaccines work really well, but scientists believe a newer vaccine may work even better and provide protection sooner (and with fewer doses).

The study involves: 10 visits over 12 months Visits are at the VEC located at BC Children’s Hospital and Women’s Health Center in Vancouver. Participants will receive 3 doses of the Hepatitis B vaccine, get blood tests at each visit, and be asked questions about your health. Females will need to be on birth control while on the study.

You will receive: Eligible participants will be reimbursed for travel/parking and receive an honorarium at each visit (between $25-$50 depending on the visit length).

Continue reading “Comparative Hepatitis B Vaccine study”

Dr. Manish Sadarangani named Sauder Chair in Pediatric Infectious Diseases

Congratulations to the VEC Director Dr. Manish Sadarangani on his recent appointment as the Sauder Chair in Pediatric Infectious Diseases at the University of British Columbia. Funded by a donation from the Sauder Family, the Chair supports research to improve the prevention, diagnosis and treatment of childhood infectious diseases.

When it comes to saving the lives of kids with serious infections, Dr. Sadarangani believes “the best option is prevention.”

 This new Chair will enable Dr. Sadarangani to further laboratory, clinical and population-based studies aimed at:

  • Understanding the immune response to vaccines
  • Developing new vaccines
  • Evaluating vaccine programs at the population level
  • Examining the incidence, causes and effects of serious childhood infections

To read more, click here.

Long Term Memory to HPV vaccine study

—-RECRUITMENT CLOSED—–

Participants needed: Women who have received either 2 or 3 doses of the HPV vaccine 8 to 10 years ago.

Why are we doing this study: Human Papillomavirus (HPV) is a common virus that can cause genital warts and can lead to cervical cancer. HPV is often described as the most common sexually transmitted infection. Vaccination with the HPV vaccine Gardasil® is known to be very good at  preventing HPV types 6, 11, 16 and 18. More research into the long term protection and immune memory years after vaccination with HPV vaccine is needed to make sure the females we vaccinate as girls are still protected as adults.

Although memory response or ‘protection’ can be measured soon after you get the HPV shot, the best way to measure long lasting protection is to give another dose, or a ‘booster’ of the vaccine years after the original shots. This is like a reminder to see how well your immune system remembers the HPV shot. We are therefore studying the immune system’s response to the HPV vaccine, 8 to 10 years after first dose. Continue reading “Long Term Memory to HPV vaccine study”

Celebrating Immunization: National Immunization Awareness Week 2017

NATIONAL IMMUNIZATION AWARENESS WEEK (#NIAW2017)

April 22nd - 29th, 2017
The VEC is celebrating National Immunization Awareness Week, an annual event to recognize the importance of immunization, by sharing a selection of our research highlights and news. You can read each story by clicking the links below

Human Vaccines Project to accelerate the development of vaccines


BC Children’s Hospital opening Canada’s first onsite immunization clinic in 2017


Cytomegalovirus (CMV) vaccine


Understanding why some parents are hesitant about vaccines


Early life immune system


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