Celebrating Immunization: NIAW 2018 and 30 Years of the VEC!

NATIONAL IMMUNIZATION AWARENESS WEEK (#NIAW2018)

April 21st - 28th, 2018
National Immunization Awareness Week, is an annual event to highlight and recognize the importance of immunization. This year also marks the 30th anniversary of the Vaccine Evaluation Centre and we wanted to share a few of the highlights that we are most proud of! #GetVax #VaccinesWork

Check out a history of vaccine research at the VEC and how you can help participate in vaccine research by clicking the link to our annual newsletter below.

 

 

 

 

 

Read our annual VEC newsletter here (and subscribe to the newsletter here!)

Comparative Hepatitis B Vaccine study

–Recruitment closed–

Participants needed: Males and females age 18 years and older in good general health who have never received the Hepatitis B vaccine

Why are we doing this study: Hepatitis B virus (HBV) is a virus that attacks the liver and can lead to cancer. The currently approved HBV vaccines work really well, but scientists believe a newer vaccine may work even better and provide protection sooner (and with fewer doses).

The study involves: 10 visits over 12 months Visits are at the VEC located at BC Children’s Hospital and Women’s Health Center in Vancouver. Participants will receive 3 doses of the Hepatitis B vaccine, get blood tests at each visit, and be asked questions about your health. Females will need to be on birth control while on the study.

You will receive: Eligible participants will be reimbursed for travel/parking and receive an honorarium at each visit (between $25-$50 depending on the visit length).

Continue reading “Comparative Hepatitis B Vaccine study”

Dr. Manish Sadarangani named Sauder Chair in Pediatric Infectious Diseases

Congratulations to the VEC Director Dr. Manish Sadarangani on his recent appointment as the Sauder Chair in Pediatric Infectious Diseases at the University of British Columbia. Funded by a donation from the Sauder Family, the Chair supports research to improve the prevention, diagnosis and treatment of childhood infectious diseases.

When it comes to saving the lives of kids with serious infections, Dr. Sadarangani believes “the best option is prevention.”

 This new Chair will enable Dr. Sadarangani to further laboratory, clinical and population-based studies aimed at:

  • Understanding the immune response to vaccines
  • Developing new vaccines
  • Evaluating vaccine programs at the population level
  • Examining the incidence, causes and effects of serious childhood infections

To read more, click here.

Long Term Memory to HPV vaccine study

—-RECRUITMENT CLOSED—–

Participants needed: Women who have received either 2 or 3 doses of the HPV vaccine 8 to 10 years ago.

Why are we doing this study: Human Papillomavirus (HPV) is a common virus that can cause genital warts and can lead to cervical cancer. HPV is often described as the most common sexually transmitted infection. Vaccination with the HPV vaccine Gardasil® is known to be very good at  preventing HPV types 6, 11, 16 and 18. More research into the long term protection and immune memory years after vaccination with HPV vaccine is needed to make sure the females we vaccinate as girls are still protected as adults.

Although memory response or ‘protection’ can be measured soon after you get the HPV shot, the best way to measure long lasting protection is to give another dose, or a ‘booster’ of the vaccine years after the original shots. This is like a reminder to see how well your immune system remembers the HPV shot. We are therefore studying the immune system’s response to the HPV vaccine, 8 to 10 years after first dose. Continue reading “Long Term Memory to HPV vaccine study”

Celebrating Immunization: National Immunization Awareness Week 2017

NATIONAL IMMUNIZATION AWARENESS WEEK (#NIAW2017)

April 22nd - 29th, 2017
The VEC is celebrating National Immunization Awareness Week, an annual event to recognize the importance of immunization, by sharing a selection of our research highlights and news. You can read each story by clicking the links below

Human Vaccines Project to accelerate the development of vaccines


BC Children’s Hospital opening Canada’s first onsite immunization clinic in 2017


Cytomegalovirus (CMV) vaccine


Understanding why some parents are hesitant about vaccines


Early life immune system


Read our annual VEC newsletter here (and subscribe to the newsletter here!)

Human Vaccines Project: Help us better understand how the immune system responds to Hepatitis B vaccine!

Why we are doing the study:
Our overall goal is to understand why some people respond better to vaccines than others, a step towards making better vaccines to prevent against infections. With this study, we are looking into how the immune system responds to Hepatitis B virus (HBV) vaccine. This vaccine is widely used to prevent liver infection, a risk at all ages. Continue reading “Human Vaccines Project: Help us better understand how the immune system responds to Hepatitis B vaccine!”

BC Children’s Hospital to open Canada’s first onsite immunization clinic

“In 1995, Dr. David Scheifele wrote a paper proposing that facilities such as B.C. Children’s Hospital should have on-site clinics where sick kids could catch up on their vaccinations. It took 21 years, but that vision is finally becoming a reality.” – The Vancouver Sun, click for article

In the Fall of 2017, BC Children’s Hospital will open the doors to Canada’s first onsite immunization clinic. The clinic will provide immunizations at no cost to children, youth and their family members visiting BC Children’s.

“This is a fantastic opportunity to protect some of the most vulnerable children in our society who come through the doors of BC Children’s Hospital every day. Offering immunizations to all family members is a simple and highly effective way to extend the impact of the clinic.” – Dr. Manish Sadarangani

For four years, the VEC has been a part of the BC Children’s on-site family flu immunization clinic offering free flu immunizations to families visiting the hospital during the months of November and December. The flu clinic has set the foundation for an onsite immunization clinic, making immunizations as accessible as possible for families and in reaching across age barriers to maximize protection of vulnerable children.

The new immunization clinic has been made possible by a generous $15 million donation from Save-On Foods.

To read the full story, click here.

Safety surveillance of the influenza vaccines

An annual flu vaccine safety survey is completed by over 20,000 people across Canada who receive their flu vaccine. The purpose of the online survey is to monitor adverse events (side-effects) after the flu shot and allows us to monitor the safety of the flu vaccine used in Canada each year.

Dr. Julie Bettinger presents findings from the safety survey at the Canadian Immunization Conference 2016. Of 200 abstracts, this study was chosen as one of the Top 10 Scientific Abstracts of 2016.

In 2015, nearly 15,000 adults responded to the online survey, most did not report any health events after the flu shot. 95% of the unvaccinated control group did not report a health events compared to nearly 97% of the vaccinated group. Overall, no safety concerns were detected for the 2015 flu vaccines.

For more information and to read the abstract, click here

This project is being conducted by Canadian National Vaccine Safety (CANVAS) network. 2016 marks the 6th year of the Vaccine Safety Survey.

Co-authors: Louis Valiquette, Brenda Coleman, Karina Top, Otto Vanderkooi, Anne McCarthy, James Kellner, Jennifer Isenor, Gaston De Serres

 

What causes changes in mothers’ vaccine hesitancy over time?

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Photo credit: US National Cancer Institute, Photographer Rhoda Baer.

In a study at the VEC, it was found that mothers who were initially hesitant about vaccines described feeling fear, anxiety, and confusion when deciding about infant immunization. One described literally having nightmares about the decision whether to vaccinate her baby.

Dr. Devon Greyson presents these findings at the Canadian Immunization Conference 2016. Of 200 abstracts, this study was chosen as one of the Top 10 Scientific Abstracts of 2016.

The 23 participants of the study included parents with school aged-children whose thoughts and feelings about vaccinations had changed since first becoming a parent. Some may have become less worried about vaccines and some, more worried.

So, what reduces vaccine hesitancy over time?

    • Extra attention and information sharing with hesitant mothers (whether or not they vaccinate)
    • Positive immunization experiences
    • Adequate attention and time to address concerns after an AEFI or chronic health condition
    • Acknowledgement that while HCPs are trusted sources, some mothers will want to verify information (consistent, verifiable vaccine safety and effectiveness information)

For more information and to read the abstract, click here
Co-authors: Dr. Julie Bettinger, Dr. Gina Ogilvie, Dr. Simon Dobson