Long Term Memory to HPV vaccine study


Participants needed: Women who have received either 2 or 3 doses of the HPV vaccine 8 to 10 years ago.

Why are we doing this study: Human Papillomavirus (HPV) is a common virus that can cause genital warts and can lead to cervical cancer. HPV is often described as the most common sexually transmitted infection. Vaccination with the HPV vaccine Gardasil® is known to be very good at  preventing HPV types 6, 11, 16 and 18. More research into the long term protection and immune memory years after vaccination with HPV vaccine is needed to make sure the females we vaccinate as girls are still protected as adults.

Although memory response or ‘protection’ can be measured soon after you get the HPV shot, the best way to measure long lasting protection is to give another dose, or a ‘booster’ of the vaccine years after the original shots. This is like a reminder to see how well your immune system remembers the HPV shot. We are therefore studying the immune system’s response to the HPV vaccine, 8 to 10 years after first dose.

The study involves: In total we will need about 2 hours of your time over the course of 1 month. You will come in for 3 visits at the VEC located at BC Children’s and Women’s Health Center in Vancouver. You will receive a booster dose of the HPV vaccine at the first visit and a blood test at each visit to measure your long term immune response to the HPV vaccine.

You will receive: Eligible participants will be reimbursed for travel/parking and a $50 honorarium at each visit.

Note: You may have been invited to take part in a similar study called the “Long Term Response to HPV vaccine study”. To be eligible for the “response” study, participants must have received the HPV vaccines as part of our BCGov01 study in 2007. To inquire about the “response” study, please click the link below.

To learn more and to see if you are eligible to participate, please contact us.